Fang Lab @ZJU
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Publications

Discover our work.

Explore publications from the Fang Laboratory spanning cell engineering, immune modulation, and biomaterial-enabled therapeutic systems.

● The Fang Laboratory Zhejiang University · Hangzhou
§ Chronological List
165

Microproteomics of CA-MRSA uncovers bioactive endogenous peptides and virulent small open reading frames

Raygoza, J.; Wozniak, J.; Tan, M.; Van, S.; Castaneda, J.; Wierzbicki, I.; Sauceda, C.; McGrosso, D.; Aguilar, J.; Dores, M.; Schilcher, K.; Wei, X.; Fang, R.H.; Trejo, J.; Corriden, R.; Zhang, L.; Horswill, A.; Gonzalez, D.

Infection and Immunity In press

164

Microrobots for pulmonary drug delivery

Li, Z.; Luan, H.; Fang, Z.; Ding, S.; Kobrin, R.; Fang, R.H.; Zhang, L.; Wang, J.

Nature Reviews Bioengineering 2026Vol. 4319-335

163

Macrophage membrane-camouflaged nanoparticles as emerging therapeutics in metabolic dysfunction-associated steatotic liver disease

Ariyathanapong, N.; Ploypradith, K.; Yoshimura, P.K.; Thedrattanawong, C.; Wuestefeld, T.; Leelahavanichkul, A.; Jin, T.; Mao, L.; Fang, R.H.; Lee, Y-A.; Thamphiwatana, S.

Smart Materials in Medicine 2026Vol. 777-92

162

Intratumoral manipulation of the immune microenvironment of solid tumors

Mao, L.; Xu, K.; Jin, T.; Yan, W.; Fang, R.H.

ACS Nano Medicine 2026Vol. 1223-249

161

Nanomedicine for oral delivery: Strategies to overcome the biological barriers

Kubiatowicz, L.; Pourafzal, N.; Zhu, A.; Guo, Z.; Fang, R.H.*; Zhang, L.* (*Co-corresponding)

Small Methods 2026Vol. 102500624

160

Bacterial membrane coating potentiates lipid nanoparticles for mRNA delivery

Wang, R.; Bao, L.; Yu, Y.; Zhang, R.; Guo, Z.; Kubiatowicz, L.; Krishnan, N.; Noh, I.; Wang, E.; Fang, R.H.; Gao, W.; Zhang, L.

Nano Letters 2025Vol. 2517074-17081

159

Neuronal membrane-functionalized biohybrid microrobots for active decontamination of neurotoxins in aqueous environments

Li, Z.; Luan, H.; Fang, Z.; Shen, W.; Yu, Y.; Ji, J.; Kobrin, R.; Zhang, J.; Neuschul, S.; Tse, W.; Ding, S.; Wang, D.; Fang, R.H.; Gao, W.; Zhang, L.; Wang, J.

ACS Nano 2025Vol. 1934123-34135

158

STING-adjuvanted outer membrane vesicle nanoparticle vaccine against Pseudomonas aeruginosa

Bjanes, E.; Krishnan, N.; Koh, T.; Ngo, A.; Cole, J.; Olson, J.; Cornax, I.; Chen, C.; Chavarria, N.; Dahesh, S.; Hannah, S.; Stream, A.; Zhang, J.; Besancon, H.; Sun, D.; Yendluri, S.; Morrill, S.; Zhou, J.; Mohapatra, A.; Fang, R.H.; Nizet, V.

JCI Insight 2025Vol. 10e188105

157

Enzymatic cellular nanoparticles deliver payloads across mucosal barriers

Kubiatowicz, L.; Pourafzal, N.; Krishnan, N.; Bao, L.; Mohapatra, A.; Gao, W.; Fang, R.H.*; Zhang, L.* (*Co-corresponding)

Bioconjugate Chemistry 2025Vol. 361767-1774

156

Picoeukaryote-based biohybrid microrobots for active delivery in the kidney

Li, Z.; Wang, D.; Luan, H.; Chang, A., Fang, Z.; Sun, L.; Ji, J.; Shen, W.; Yu, Y.; Yan, Y.; Ding, S.; Zhang, J.; Zhang, Y.; Peng, Y.; Fang, R.H.; Gao, W.; Zhang, L., Wang, J.

Science Advances 2025Vol. 11eadw8578

155

Macrophage-mimicking nanodiscs for treating systemic infection caused by methicillin-resistant Staphylococcus aureus

Feng, K.; Sun, L.; Zhou, Z.; Zhang, J.; Fang, R.H.; Gao, W.; Zhang, L.

Science Advances 2025Vol. 11eadw7511

154

Nanoparticle approaches for manipulating cytokine delivery and neutralization

Wang, R.; Kubiatowicz, L.; Zhang, R.; Bao, L.; Fang, R.H.*; Zhang, L.* (*Co-corresponding)

Frontiers in Immunology 2025Vol. 161592795

153

Universal prophylactic antitumor vaccination using stem cell membrane-coated nanoparticles

Krishnan, N.; Zhou, J.; Mohapatra, A.; Ventura, C.; Duan, Y.; Lee, J.; Hoenig, J.; Nizet, O.; Gao, W.; Fang, R.H.*; Zhang, L.* (*Co-corresponding)

Advanced Materials 2025Vol. 372501616

152

Hepatic endoplasmic reticulum-derived nanodiscs for broad-spectrum drug detoxification

Sun, L.; Feng, K.; Bai, D.; Yu, Y.; Shen, W.; Zhang, J.; Fang, R.H.; Gao, W.; Zhang, L.

Biomaterials 2025Vol. 318123188

151

Modular functionalization of cellular nanodiscs enables targeted delivery of chemotherapeutics into tumors

Noh, I.; Guo, Z.; Wang, R.; Zhu, A.; Krishnan, N.; Mohapatra, A.; Gao, W.; Fang, R.H.*; Zhang, L.* (*Co-corresponding)

Journal of Controlled Release 2025Vol. 378145-152

150

Aptamer-encapsulated cellular nanoparticles for neurotoxin neutralization

Kai, M.; Shen, W.; Wang, D.; Yu, Y.; Zhang, J.; Sun, L.; Fang, R.H.; Gao, W.; Zhang, L.

Advanced Healthcare Materials 2025Vol. 142403539

149

Inhalable biohybrid microrobots: A non-invasive approach for lung treatment

Li, Z.; Guo, Z.; Zhang, F.; Sun, L.; Luan, H.; Fang, Z.; Dedrick, J.; Zhang, Y.; Tang, C.; Zhu, A.; Yu, Y.; Ding, S.; Wang, D.; Chang, A.; Yin, L.; Russell, L.; Gao, W.; Fang, R.H.; Zhang, L.; Wang, J.

Nature Communications 2025Vol. 16666

148

Cellular nanoparticles treat coronavirus infection in vivo

Yu, Y.; Silva-Ayala, D.; Zhou, Z.; Peng, Y.; Fang, R.H.; Gao, W.; Griffiths, A.; Zhang, L.

Nano Letters 2024Vol. 2415136-15141

147

Towards multifunctional robotic pills

Mundaca-Uribe, R.*; Askarinam, N.*; Fang, R.H.*; Zhang, L.; Wang, J. (*Co-first)

Nature Biomedical Engineering 2024Vol. 81334-1346

146

Viral and nonviral nanocarriers for in vivo CRISPR-based gene editing

Guo, Z.; Zhu, A.; Fang, R.H.*; Zhang, L.* (*Co-corresponding)

Nano Research 2024Vol. 178904-8925

145

Neuronal membrane-derived nanodiscs for broad-spectrum neurotoxin detoxification

Wang, D.; Sun, L.; Shen, W.; Haggard, A.; Yu, Y.; Zhang, J.; Fang, R.H.; Gao, W.; Zhang, L.

ACS Nano 2024Vol. 1825069-25080

144

Macrophage-mimicking cellular nanoparticles scavenge proinflammatory cytokines in specimens of patients with inflammatory disorders

Zhou, Z.; Mukundan, N.; Zhang, J.; Wu, M.; Zhang, Q.; Wang, D.; Fang, R.H.; Gao, W.; Zhang, L.

Advanced Science 2024Vol. 112401423

143

A genetically engineered neuronal membrane-based nanotoxoid elicits protective immunity against neurotoxins

Guo, Z.; Zhu, A.; Wei, X.; Jiang, Y.; Yu, Y.; Noh, I.; Gao, W.; Fang, R.H.*; Zhang, L.* (*Co-corresponding)

Bioactive Materials 2024Vol. 38321-330

142

Biohybrid microrobots regulate colonic cytokine and epithelium barrier in inflammatory bowel disease

Li, Z.; Duan, Y.; Zhang, F.; Luan, H.; Shen, W.; Yu, Y.; Xian, N.; Guo, Z.; Zhang, E.; Yin, L.; Fang, R.H.; Gao, W.; Zhang, L.; Wang, J.

Science Robotics 2024Vol. 9eadl2007

141

Rapid functionalisation of cell membrane-coated nanoparticles using a modular approach

Krishnan, N.; Fang, R.H.*; Zhang, L.* (*Co-corresponding)

Clinical and Translational Medicine 2024Vol. 14e1721