Research

About Our Research

Overall Mission

At the Fang Laboratory at Zhejiang University, we focus on developing innovative therapeutics using nanomaterials, biomaterials, and cellular engineering. Our work emphasizes biomimetic design principles, drawing on natural blueprints refined through the highly selective process of evolution. This approach enables the streamlined development of biomedical platforms that interact effectively with biological systems, maximizing their therapeutic potential. Our talented research team leverages these advances to address a range of medical challenges, with the ultimate goal of translating our discoveries into practical healthcare solutions.

Schematic illustration of how cell membrane-coated nanoparticles are fabricated in nanomedicine research

Research Directions

Immuno-engineering

Nanomaterials and biomaterials offer innovative solutions to enhance immune responses. By engineering platforms to deliver both antigenic components and potent immunological adjuvants, we can design vaccines capable of eliciting robust and diverse immune responses. This approach is particularly promising for addressing a wide array of challenges, from infectious diseases to cancer. The technologies we are developing not only improve vaccine efficacy but also facilitate the development of personalized immunotherapy strategies.
Depiction of an immune cell floating

Biomimetic delivery

Cells have evolved over millions of years to perform specific functions, such as site-specific binding and biological interfacing. Our technologies leverage this evolutionary advantage by employing various types of cells and their derivatives, harnessing their natural affinities and interactions. This approach enables precise biological modulation, enhancing both efficacy and specificity. Our innovative biomedical platforms pave the way for advanced therapeutic applications.
Illustration of a cell membrane vesicle